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Metabolic disorders were also observed in offspring of dams exposed to PS MP by drinking water during pregnancy [50, 51] and lactation [50]
a number of other patents and patent applications contain prophetic disclosures of combination therapy where one agent is a melanocortin receptor agonist and a second agent is a PDE-5 inhibitor
Of that group, 54.6% lost at least 10% of their weight, 36% lost at least 15%, and 18.4% lost 20% or more
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