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Different strategies were used to improve the peptide half-life including sequence modifications (exenatide, lixisenatide) 36,37 , conjugation to molecules with propensity to bind albumin (liraglutide, semaglutide) 36,37 , fusion to large proteins (albiglutide, dulaglutide, efpeglenatide) 36,37 , side chain cross linking 38,39 , and -residue replacement 40,41,42 (Fig
Together, they can offer a powerful, two-pronged attack on high blood sugar for people with type 2 diabetes who need more intensive therapy
Adems, la marca blanca tambin ofrece menos transparencia en la obtencin, pruebas y garanta de calidad en comparacin con las opciones de fabricacin personalizadas o internas
