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GLP-1 Receptor Agonist Use Linked to Reduced Risks for Substance Use Disorder MONDAY, March 9, 2026 -- The use of glucagon-like peptide-1 (GLP-1) receptor agonists is associated with reduced risks for developing substance use disorders (SUDs), according to a study published online March 4 in The BMJ

Compared with less selective secre20260613-mnav1ogue peptides, ipamorelin has been utilized in preclinical models to support structure-activity relationship (SAR) studies and to help isolate GHSR-linked signaling from broader, multi-receptor secre20260613-mnav1ogue activity in vitro and in vivo animal systems

However, due to limitations in methodology and potential bias, the certainty of the evidence is low

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