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Key Points: GI symptoms are the most common adverse effects, ranging from expected nausea and vomiting to gastroparesis and, rarely, functional obstruction Delayed gastric emptying has important airway implications and a cautious approach to airway management is warranted Biliary disease is one of the most clinically significant complications, particularly early in treatment and with rapid weight loss Pancreatitis is rare, and current evidence does not support a strong causal relationship EDKA and AKI are uncommon but important to recognize in the right context Conclusions: GLP-1 receptor agonists have transformed the management of diabetes and obesity, with clear benefits in weight loss, glycemic control, and cardiovascular outcomes

Im down to 285." While Barkley said his doctor told him he's now at a "good, healthy weight," he's hoping to go back on Mounjaro and lose another 15 pounds

The quantity of medication should be reasonable for the trip durationtypically limited to 30-90 days depending on the country

Semaglutide improved Kansas City Cardiomyopathy Questionnaire (KCCQ) scores by 7 to 8 points more than placebo, produced 13% weight loss, improved six-minute walk distance by approximately 20 meters, and reduced C-reactive protein (a marker of inflammation) by about 40%