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Human studies have mainly described pharmacokinetics, safety, and tolerability, rather than demonstrating strong clinical effectiveness
The practical consequence is that the GHK-Cu complex may partially degrade in the presence of high-concentration ascorbic acid on the skin surface, and the free copper(I) could be mildly pro-oxidant
This delayed pattern also appears in BPC-157 recovery timelines, where improvement often emerges weeks in rather than immediately
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