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In vitro studies have examined its interaction with fibroblast and keratinocyte cell preparations, documenting that the GHK-Cu complex stimulates collagen synthesis in cultured fibroblasts independently of changes in cell number [1], and that GHK-Cu increases matrix metalloproteinase-2 (MMP-2) protein and mRNA levels in fibroblast cultures
A similar dissociation was also reported by Xin et al
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Heisterkamp, N., Groffen, J., Warburton, D
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