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Keep reconstituted solutions refrigerated (2-8C) only

Phase 2 trial results (48 weeks, adults with obesity): 1 mg dose: 7.2% body weight loss 4 mg dose: 12.9% body weight loss 8 mg dose: 17.3% body weight loss 12 mg dose: 24.2% body weight loss Placebo: 1.6% body weight loss Phase 3 TRIUMPH-4 results: 9 mg dose: 20.0% body weight loss (22.9 kg / 50.5 lbs) 12 mg dose: 23.7% body weight loss (27.2 kg / 60.0 lbs) Placebo: 4.6% body weight loss In a separate phase 3 analysis, retatrutide at the highest dose achieved up to 28.7% weight loss

These combined properties have led to increasing interest in its therapeutic potential across various clinical contexts, including the health of the cardiovascular system, metabolic syndrome, gastric ulcers, cancer, and neurodegenerative diseases (Copat et al., 2025

Foods containing protein include chicken, beef, nuts, fish, and beans