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However, some of the widely used affinity tags, such as the His-tag, exhibit several drawbacks and limitations, since they can increase the risk of distorting the natural conformation of the target protein or necessitate stringent elution and wash conditions affecting the yield of the target protein
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Patients with type 2 diabetes who are also taking insulin or sulfonylureas should be monitored closely for hypoglycemia risk when discontinuing Zepbound or switching to alternative medications
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