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It has a dual-action design, mimicking the action of two incretin hormones involved in blood glucose control: Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP)
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Introduction Clinical features Causes Investigations Treatment A melanotic macule is a well-defined, oval, brown to black, flat patch usually found on the central third of the lower lip, however it can more rarely occur on the penis or vulva