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HansotiaTBaggioLLDelmeireDHinkeSAYamadaYTsukiyamaKet al
In recombinant cell systems, it activates GIPR with potency similar to native GIP and GLP-1R with reduced but pharmacologically meaningful potency relative to native GLP-1
This brings us to our first contraindication (a factor that makes you ineligible): anyone with a history of thyroid tumors or a condition called multiple endocrine neoplasia, type 2 (MEN 2)
doi:10.1016/j.neuroscience.2015.05.023 47
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