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Novo Nordisk originally developed the active ingredient to treat type 2 diabetes
Demographic variables included age, sex and Tanner stage
Important safety considerations include: Increased hypoglycaemia risk when used with insulin or sulfonylureas (dose adjustments of these medications may be needed) Potential worsening of diabetic retinopathy with rapid improvement in blood glucose control, particularly with semaglutide Need for monitoring in patients with pre-existing retinopathy The MHRA continues to monitor the safety profile of these agents
Among the group receiving sub-Q semaglutide plus counseling, weight loss over 68 weeks was 16 percent compared to less than 6 percent in the control group
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