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However, the mitochondrial ROS are also responsible for DNA damage, which causes the abundant consumption of NAD + by PARPs

Activation of the NRF2 signaling pathway by copper-mediated redox cycling of para- and ortho-hydroquinones

If you are researching the epitalon telomere longevity peptide , here is the direct answer: epitalon activates telomerase and extends telomere length in human cell studies, including a 2025 independent replication published in Biogerontology