glp 1 and dementia prevention GLP-1 Drug Fails to Quell Alzheimer's in Novo Nordisk Trials GLP-1 and the Degenerating Brain:

The ACHIEVE-3 head-to-head data favor orforglipron on both efficacy and convenience endpoints

Quick math for common doses at 2.5 mg/mL: 0.25 mg: 0.25 / 2.5 x 100 = 10 units 0.50 mg: 0.50 / 2.5 x 100 = 20 units 1.0 mg: 1.0 / 2.5 x 100 = 40 units 1.7 mg: 1.7 / 2.5 x 100 = 68 units 2.4 mg: 2.4 / 2.5 x 100 = 96 units If you reconstituted with 3.0 mL instead (1.67 mg/mL), the same doses become 15, 30, 60, 102, and 144 units respectively

Email and portal messages get polite 24-hour replies, but the phone line goes straight to voicemail with no callback in testing

First, during manufacturing, and again when you mix it