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FDA's evaluation concluded that the criteria weighed against placement on the list, citing inadequate physicochemical characterization, immunogenicity concerns from impurities and aggregates, lack of clinical effectiveness data for any approved use, and absence of published human exposure data for the proposed subcutaneous and topical routes

B12 Self-Injection Is Easy Learning how to self administer B12 injections unlocks a new level of independence

Quality Control Quality control for BPC 157 is a significant concern due to its unregulated status

Even with B12 in the diet, absorption depends on stomach acid and a protein called intrinsic factor, both of which decline with age and with certain medications