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The resulting pentapeptide demonstrated potency comparable to GHRP-6 in multiple models: EC = 1.3 nmol/L in rat pituitary cells, ED = 80 nmol/kg in anesthetized rats, and ED = 2.3 nmol/kg in conscious swine
IGF-1 LR3 has been extensively used in muscle satellite cell research, bone biology, neuroprotection models, and metabolic signaling studies as a surrogate for sustained IGF-1 receptor activation
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