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Notably, the orientation of ECD is distinct from that of GLP-1-bound GLP-1R with a rotation angle of 97.4 degrees: the former pointed from ECL2 to TM1-TM2 and the latter oriented from ECL1 to TM5-TM6 (Fig
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A recent study has shown that the influenza virus matrix 1 protein can induce the production of proinflammatory cytokines and cellular ROS as well as trigger cell death through the activation of TLR4 signaling 28
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