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Circulation 129(5):587597 van Bommel EJ, Muskiet MH, van Baar MJ, Tonneijck L, Smits MM, Emanuel AL et al (2019) The renal hemodynamic effects of the SGLT2 inhibitor dapagliflozin are caused by post-glomerular vasodilatation rather than pre-glomerular vasoconstriction in metformin-treated patients with type 2 diabetes in the randomized, double-blind RED trial
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Absorption varies depending on: Dosage Formulation Individual metabolism Oral supplements are generally safer than injections but should still be used cautiously
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