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Absence of GH-Receptor Signaling Full-length hGH binds GH receptors in the liver, triggering JAK2-STAT5 phosphorylation and IGF-1 synthesis [5]
It is not intended for human consumption, therapeutic use, or as a food or drug product
AOD-9604 is the more-studied stabilized version Compound Human Growth Hormone (somatropin) Class Full-length recombinant hGH FDA Status FDA-approved for specific indications (GH deficiency, certain growth disorders, AIDS wasting) Evidence Strength Strong human evidence for approved indications
Systematic Review Orthopaedic Sports Medicine (2025) The 2025 systematic review by Vasireddi, Hahamyan et al
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