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ER stress response in human cellular models of senescence

The authors validated that cisplatin could be gradually liberated from Fe-DSCP-PEG-cRGD with time and the structure of nanoparticles was largely collapsed (Figure 3C)

Furthermore, it has recently been reported that the induction of endoplasmic reticulum (ER) stress response, lens epithelial cell (LEC) apoptosis, and epithelial-mesenchymal transition (EMT) are implicated in the development of diabetic cataracts 15,16,17