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Conclusion This case report demonstrates that the combination of prolonged water fasting and a GLP-1 receptor agonist is a safe and effective method for short-term substantial weight loss in patients with severe obesity for the purpose of pre-procedural optimization prior to bariatric surgery, and may result in the improvement of multiple chronic diseases including hypertension, insulin resistance, anemia, depression, and diastolic heart failure
Rare but serious side effects appear comparable between medications
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