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Gradual exposure allows the skin to darken evenly while minimizing irritation
Developed at the University of Arizona, it is a cyclic lactam analogue of -MSH with the amino acid sequence Ac-Nle- cyclo [Asp-His--Phe-Arg-Trp-Lys]-NH 2
Concentrations up to 100% in guinea pig tests found it to be non-sensitizing and completely safe for use in cosmetics
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