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This broad gene-level effect suggests GHK-Cu may influence healing at a more fundamental level than peptides with narrower mechanisms
A trial was conducted with a dose escalation design comprising 5 different infusion rates (4.21, 14.02, 42.13, 84.27 and 140.45 nmol/kg over 15 minutes) with eight healthy male subjects at each dose level
The peptide also modulates MMP activity and expression, creating a balanced proteolytic environment that allows removal of damaged, fragmented collagen while protecting newly synthesized fibers
Park JM, Lee HJ, Sikiric P, Hahm KB
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