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We employ a pancreatic -cell specific EGFR null mouse (-EGFR fx/fx ) and exogenous exendin-4 treatment to show a role for -cell EGFR in -cell mass, islet size, -cell proliferation, and insulin content
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doi: 10.3389/fendo.2023.1080969 Received 26 October 2022 Accepted 31 January 2023 Published 21 February 2023 Volume 14 - 2023 Edited by Jeff M
The feedback inhibition of IGF-1 on further GH secretion stayed intact, preventing the GH excess that drives insulin resistance with direct injection
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