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In protocol 2, we give 3.6 mM of NAC per hour for 10 hours beginning 2 hours after the 22 g APAP dose
The hypothalamus is already producing rhythmic GHRH pulses
Conclusion and future perspectives As shown in the Figure 4 , cysteine has different fates including the synthesis of cysteine-derived molecule, sulfur/carbon metabolic reprogramming, and venue for post-translational protein modification of various proteins or discovery of drug inhibitors
The no-observed-adverse-effect level (NOAEL) was set at 50mg/kg, the highest dose tested
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