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Description

E.Rosales-MendozaS.ChangS.HaudenshieldJ

REDEFINE 1 and REDEFINE 2 ran 68 weeks, with the first ~16 weeks dedicated to dose titration

Their safety and effectiveness haven't been established

At higher doses of MEDI4166, significant reductions in triacylglycerol and lipoprotein(a) and increases in HDL-cholesterol levels were observed compared with placebo (Table 6)