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Ferulic acid (FA), the main active component isolated from Angelica sinensis , has been documented to increase the levels of GSH and the expression of GPX in the myocardium by upregulating AMPK2 and activating Nrf2 signaling [41, 165]
For instance, electrophilic compounds such as sulforaphane from cruciferous vegetables or the flavonoid quercetin from apples can directly react with critical cysteine residues on the Keap1 protein
2013 Jun;378(1-2):1-8
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