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One unexpected serious adverse reaction occurred in a NAC-treated patient caused by an erroneous iv infusion rate (1.5g-loading dose-15 min followed by 7.5 g delivered over 3h15min instead of 4 h), causing chest tightness, despite stable vital signs, which was resolved by corticosteroids and discontinuation of iv NAC
Most often, the increase in heart rate is smallabout 2 to 4 beats per minute
it should not be used by people with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
Cell B 42 , 3951 (2010)
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