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Notably, the loading of BBR into nanoparticle carriers could delay the release of BBR compared with free BBR and facilitate steady drug release for about 24 h, which could overcome bioavailability barriers in humans
A bridge demonstration program launches in July 2026, allowing initial enrollment and testing of program logistics
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In addition, despite addressing the degradation on production, the peptide component of this IL17A/IL-22 fusion was still prone to cleavage after in vivo administration 31
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