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The amyloidogenic core sequence of hIAPP (residues 2029, known as the FGAILS region) has been substituted to eliminate -sheet aggregation propensitya critical requirement for generating a stable, injectable research compound

Where BPC-157 tends to be more targeted toward connective tissue and the gut, TB-500 has broader systemic effects muscles, fascia, cardiac tissue, nerve healing

Use appropriate laboratory safety procedures when handling

The study addressed two questions: whether the fragment retained activity when delivered enterally rather than parenterally, and whether the effects observed in rodent models translated to human adipose tissue at the cellular level