they also suppress platelet activity, which may further contribute to cardiovascular protection ( 3.4 Complications and side effects of GLP-1 RAs Common side effects associated with GLP-1 receptor agonists (GLP-1 RAs) include gastrointestinal symptoms such as nausea (2560%), diarrhea, and vomiting (515%) ( While some studies have suggested a possible association between GLP-1 RAs and acute kidney injury (AKI), this has not been confirmed and appears to occur primarily in patients with underlying risk factors such as dehydration or severe gastrointestinal symptoms ( GLP-1 RA therapy should be discontinued under specific clinical conditions to minimize risk
However, GLP-1RA are contraindicated for use in individuals with predisposition to MEN2 and medullary thyroid carcinoma (112)
Ozempic can lower the risk of major cardiovascular events, such as stroke, heart attack, or death in adults with type 2 diabetes who also have heart disease
Emily Mullin: We know, though, that with any drug, there are differences in response rates, but I think there's been such a spotlight on these anti-obesity drugs, because their results have been really hyped