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In contrast, the beneficial effects of SGLT2 inhibitors on albuminuria and eGFR decline in DKD were demonstrated by EMPA-REG OUTCOME (Wanner et al., 2016), CANagliflozin cardioVascular Assessment Study (CANVAS) ( Statements Author contributions DK and YT wrote and revised the manuscript
COP1 binds its substrates through their conserved Val-Pro (VP) motifs 43,44,45
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