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No one has asked him to present on MOTS-c so far, and if they did, he said he would advise against it and instead appeal for researching funding and accelerated clinical trials
Transitioning from weight loss to maintenance Determining goal weight achievement: Lost 10-12% body weight (cagrilintide alone) Lost 15-25% body weight (CagriSema) Weight stable for 4-8 weeks Satisfied with current weight Ready to focus on maintenance Maintenance dose options comparison: Option 1: Continue same dose Keep cagrilintide at 2.4mg weekly Ensures no regain Most conservative approach Highest cost Option 2: Reduce dose slightly Decrease to 1.8-2.0mg weekly Monitor weight for 4 weeks If stable, maintain If gaining, increase back 20-25% cost savings Option 3: Try every 10 days Instead of weekly, inject every 10 days Effectively 30% dose reduction Some maintain weight this way Requires close monitoring Recommendation: Try Option 2 first (reduce to 1.8-2.0mg)
Pharmacologists call this a flattening dose-response curve, and it carries enormous practical implications
As the body ages, natural levels of GHK-Cu decline, which contributes to thinning skin, loss of elasticity, slower regeneration, dullness, and more visible signs of aging
