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Withhold SYNJARDY or SYNJARDY XR, if possible, in temporary clinical situations that could predispose patients to ketoacidosis
While many weight loss medications only target the GLP-1 receptor, tirzepatide is a dual agonist , meaning it targets both GLP-1 and GIP receptors
DSIP does not have comparable long-term safety evidence, and the FDA has raised concerns about insufficient safety data and quality-control issues involving compounded DSIP products
Several recent CVOTs have shown that GLP-1RAs can reduce the decline of estimated GFR (eGFR) and delay the onset of the occurrence of proteinuria in patients with T2DM [4, 22, 26, 46, 47]
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