Abbreviations GLP-1: Glucagon-like peptide 1 GIP: Glucose-dependent insulinotropic polypeptide GLP-1R: Glucagon-like peptide 1 receptor GIPR: Glucose-dependent insulinotropic polypeptide receptor ASCVD: Atherosclerotic cardiovascular disease HF: Heart failure HFpEF: Heart failure with preserved ejection fraction HFrEF: Heart failure with reduced ejection fraction T2DM: Type 2 diabetes mellitus EF: Ejection fraction LVEF: Left ventricular ejection fraction LVEDV: Left ventricular end-diastolic volume LVESV: Left ventricular end-systolic volume LVSV: Left ventricular stroke volume CO: Cardiac output CI: Cardiac index BSA: Body surface area LVIDs: Left ventricular internal diameter in systole LVIDd: Left ventricular internal diameter in diastole LVFS: Left ventricular fractional shortening LVAWTs: The thickness of the left ventricular anterior wall in systole LVAWTd: The thickness of the left ventricular anterior wall in diastole LVPWTs: The thickness of the left ventricular posterior wall in systole LVPWTd: The thickness of the left ventricular posterior wall in diastole LV: Left ventricular mass RWT: Relative wall thickness LVRi: Left ventricular remodelling index AngII: Angiotensin II Veh: Vehiculum Lira: Liraglutide TZP: Tirzepatide ECG: Electrocardiography References Ryan DH, Lingvay I, Colhoun HM, Deanfield J, Emerson SS, Kahn SE, et al

8-(3-(R)-aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydropurine-2,6-dione (BI 1356), a highly potent, selective, long-acting, and orally bioavailable DPP-4 inhibitor for the treatment of type 2 diabetes
Some commercial plans cover it when BMI and weight-related condition criteria are met
Dry mouth Semaglutide effects the salivary glands in the mouth