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Aged mice in the study showed signs of endothelial dysfunction, increased vascular stiffness, and impaired coronary microcirculation, which are hallmarks of HFpEF [17]
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In Taiwans National Health Insurance program, the cost of a GLP-1RA (e.g., liraglutide) can be up to 7 times that of insulin (e.g., insulin glargine) per treatment cycle (e.g., US$108.6 versus US$15.4 per month) [6]
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