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Rights and permissions About this article Cite this article GLP-1-mediated synaptic plasticity in feeding regulation is modulated by energy state
It's a chain of 15 amino acids linked together in a precise sequence (a pentadecapeptide)
Oral small molecules: Orforglipron
In a study of 80 obese people with type 2 diabetes receiving semaglutide and dulaglutide, a 20% reduction in the thickness of EAT was observed (62) One meta-analysis demonstrated the cardioprotective effects of GLP-1 RAs, showing reductions in blood pressure and lipid profile, with a significant increase in HDL levels (63)
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