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AT A GLANCE Originally FDA-approved for type 2 diabetes, glucagon-like peptide-1 receptor agonists (GLP-1 RAs) also lead to sustained weight loss and have revolutionized diabetes and obesity management
We also concluded the current ways of lowering insulin levels and clinical advances targeting the insulin signal pathway in pancreatic cancer
In the rat model of neuropathic pain induced by CCI, Fer-1 upregulates GPX4 expression, downregulates ACSL4 expression, and decreases the content of iron in the spinal cord, while erastin has the opposite effect
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