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Nevertheless, the kinetic data for our mutants and rate constants for ScGrx7 and PfGrx between 10 5 10 6 M 1 s 1 are too slow for a diffusion-controlled reaction and point towards important short-lived enzymesubstrate interactions and rate-limiting re-orientations of the substrate at the enzyme surface
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This effect often results from the potent antioxidant activity clearing oxidative stress
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