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The comparator arm was placebo, a GLP-1 RA (subcutaneous administration of semaglutide 1 mg once-weekly) and basal insulin in three [18, 19, 22], one [24, 25] and two trials [20, 21], respectively, while one trial included both a placebo arm and a GLP-1 RA arm (dulaglutide 1.5 mg once-weekly) [23]

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Blood test markers to discuss with a clinician Marker IGF-1 Why it matters Shows the downstream signal after repeated GH-pulse stimulation

It may contribute additional phytochemicals, but its harder to evaluate than the standardized extract because root powder doesnt offer the same level of dose consistency or clinical traceability