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While its expression pattern varies across tumor types, CHAC1 is frequently upregulated in aggressive malignancies, such as breast and ovarian cancer, where it correlates with advanced tumor differentiation and potentially serves as a prognostic marker

Injectable formulations benefit from site rotation to minimize local reactions

Based on the patients medical history, histopathological examination, immunohistochemistry, and even gene detection, it was determined that there was a correlation between the 2 parts tumors, ultimately leading to a revised diagnosis of ankle metastatic amelanotic MM, that is metastatic desmoplastic melanoma

Ishihara H, Yamaguchi S, Nakao I, et al