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Mechanistically, activation of GLP-1R by GLP-1 or exenatide phosphorylates STAT3, which drives human monocyte-derived macrophages to develop an M2 phenotype marked by increased expression of CD163, CD204, and IL-10 [86]
While both can lead to significant weight loss, their efficacy and side effect profiles differ
The way your body processes an SSRI while taking a GLP-1 may differ from someone elses experience
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