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Cost-Effectiveness: Outsourcing with a third party manufacturer such as H&I Critical Care saves the company from huge amounts of investments put into infrastructure, machinery, and labor, thereby reducing overall cost of operation

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Indeed, lead has been shown to cause gut microbiota dysbiosis and hepatic metabolic disorder in zebrafish (Xia et al., 2018a), and a 2020 study established that cadmium exposure altered the intestinal microbiota in freshwater crayfish ( Procambarus clarkia ) with regards to richness, diversity and composition, while also causing histological changes in the intestines (Zhang et al., 2020b)