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You might wonder how a pill works if you lack intrinsic factor: at very high oral doses, a small amount of B12 can be absorbed directly through the gut wall via passive diffusion, bypassing the need for intrinsic factor entirely [1] [3]
Balihodzic A, Prinz F, Dengler MA, Calin GA, Jost PJ, Pichler M (2022) Non-coding RNAs and ferroptosis: potential implications for cancer therapy
5.4 Probiotic adhesion to the mucosa and host interaction Probiotics play an important role in regulating the synthesis and structural composition of the protective mucus layer that coats the intestinal epithelium (117)
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