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Annualized, that's a difference that can reach into the thousands for patients on long-term GLP-1 therapy, which semaglutide typically is

Common transition effects include increased hunger signals and food cravings, particularly if leptin and ghrelin imbalances remain unaddressed, as well as emotional challenges around eating and portion control, she says

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Secretion of glucagon-like peptide-1 (GLP-1) in type 2 diabetes: what is up, what is down