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StructureActivity Relationship for Small Molecule Inhibitors of Nicotinamide N-Methyltransferase Journal of Medicinal Chemistry, 2017
B is needed for the production of neurotransmitters such as GABA, serotonin, and dopamine, and for glycogen breakdown and hemoglobin synthesis
via Medical News Today
While the condition is the major cause of poor vitamin B 12 status in the elderly population, it is usually associated with atrophic gastritis, a chronic inflammation of the lining of the stomach that ultimately results in the loss of glands in the stomach (atrophy) and decreased stomach acid production (see Atrophic gastritis)
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