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Nobody disputes the biochemistry
another barrier-enhancing mechanism is where Akkermansia induces Paneth cells to produce antimicrobial peptides, and SCFAs from intestinal mucin glycoproteins are absorbed in the colon as an energy source for colonic cells, inducing regulatory T cells and exerting anti-inflammatory effects (Everard et al., 2013
As dose increases to surpass the amount required to maintain homeostasis, overdose toxicity can ensue
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