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Without the correct amount of insulin, the body is unable to properly metabolize carbohydrates, fats, and proteins

It is also contraindicated in patients with a history of pancreatitis or gastrointestinal issues since it increases gastrointestinal emptying time which can intensify symptoms

If the concentration is too low, it may fail to provide any therapeutic effect, and if too high, it could have serious consequences for patients

Published research describes SNAC as raising local gastric pH and transiently increasing membrane permeability, which facilitates absorption of the peptide across the gastric epithelium