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Whereas low cytosolic Ca 2+ concentrations facilitate IP 3 binding and channel opening, high cytoplasmic Ca 2+ concentration inhibits the IP 3 R

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Citation: Ting KKY, Floro E, Dow R, Jongstra-Bilen J, Cybulsky MI, Rocheleau JV (2024) Measuring the rate of NADPH consumption by glutathione reductase in the cytosol and mitochondria

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Therefore, older advice goes out of date fast

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PMID 18585399

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