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Badenhorst T, Svirskis D, Merrilees M, et al

1,13 However, studies have found that 35% of patients experience local recurrences, suggesting that adjuvant radiation should be considered more broadly, particularly given the sensitive locations in which these neoplasms often arise that prohibit meaningful salvage operations

The result is an effective half-life of around 6 days, which supports once-weekly subcutaneous administration in the published research dose-finding work