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For example, deguelin can suppress tumor angiogenesis on vascular endothelial cells by decreasing autocrine VEGF and repressing HGF-induced c-Met signaling pathways, thereby inhibiting HCC progression (Li et al., 2018)
Real-Time Quantitative PCR After drug treatment at the indicated time, total RNA from cells and hippocampal tissues were extracted using TRIzol reagent (Invitrogen, United States) following the manufacturers procedures
Moreover, disruption of TRIM37 ligase activity or mutation of TRIM28 ubiquitination sites compromises PGC maintenance
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